CD10 (Membrane Metalloendopeptidase) (MME/1892), 1mg/mL
CD10 (Membrane Metalloendopeptidase) (MME/1892), 1mg/mL thumbnail 1
GTR00947973

CD10 (Membrane Metalloendopeptidase) (MME/1892), 1mg/mL

antibody-polyclonal-caspase

Description

CD10 (also known as Common Acute Lymphocytic Leukemia Antigen (CALLA) ) is a type II transmembrane protein. It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML) . It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Synonyms
CD10; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen (CALLA) ; Enkephalinase; gp100; Membrane metalloendopeptidase; Neutral endopeptidase

Description

CD10 (also known as Common Acute Lymphocytic Leukemia Antigen (CALLA) ) is a type II transmembrane protein. It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML) . It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications Table·product-specifications

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